An image of mitochondrial toxicity mechanism determination through metabolomic analysis and bioinformatics

Indicator molecule determined for mitochondrial toxicity arising from side effects of medicine -- High hopes of application to a new method of toxicity assessment in drug development -- Kindai University

- Conducted metabolomic analysis on human hepatoma cell lines which were exposed to mitochondrial toxic compounds - Utilized bioinformatics to identify the indicator molecule which determines the mechanism of mitochondrial toxicity - These results could be applied to a new toxicity assessment method in the drug development field