kindai20230927

Alyref and Gabpb1 -- Gene Targets to Overcome Preimplantation Arrest in Cloned Embryos Discovered -- Kindai University

Japanese scientists have now discovered the specific genes responsible for this phenomenon. Their findings show that the incomplete activation of the Alyref and Gabpb1 genes causes early embryonic arrest, while the supplementation of these genes supports normal embryonic growth. These findings could guide genetic manipulation strategies to optimize animal cloning.