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Ground Breaking Development of World’s First CurativeTreatment of Intractable Hepatocellular Carcinoma Path to Establishment of Standard Treatment of Hepatocellular Carcinoma - Kindai University

Senior Administrator Masatoshi Kudo of Kindai University Faculty of Medicine, Department of Gastroenterology and Hepatology, with his research group has invented a new method (LEN-TACE) of treating patients with intractable multinodular or large liver cancers, particularly those with near advanced liver cancer.

Top row: Pancreatic inflammation observed by hematoxylin & eosin staining    Bottom row: pancreatic fibrosis observed by sirius red staining

Mechanism Behind Onset of Autoimmune Pancreatitis Caused by Changes in Intestinal Flora Elucidated Development of New Treatment Methods Expected - Kindai University

Kindai University have discovered, for the first time in the world, a deep link between changes in the maintained balance of accumulated co-existing intestinal flora (bacteria) and immune responses in patients with chronic disease of the pancreas caused by autoimmune pancreatitis. This paper will be published online at midnight Japan time, July 10th, 2019, in “International Immunology”.

Successful Construction of Artificial Cell Nuclei Inside of Fertilized Egg; A World First One Part of the Cell Nuclei Structure Formation Mechanism Elucidated - Kindai University

Successful Construction of Artificial Cell Nuclei Inside of Fertilized Egg; A World First One Part of the Cell Nuclei Structure Formation Mechanism Elucidated - Kindai University

A Research group comprised of Kindai University’s Faculty of Biology-oriented Science and Technology , the National Institute of Information and Communications Technology and Osaka University have focused their attention on the building blocks of life, DNA, and in a world first, the group has artificially created cell nuclei structures in living mouse fertilized eggs.

Immuno-pathogenesis of Chronic Pancreatic Diseases Uncovered Applications expected for the treatment of pancreatic diseases and preventive measures for pancreatic cancer - Kindai University

Until now, the barely understood immuno-pathogenesis for chronic inflammation of the pancreas has been uncovered. The pathogenic immune response that is common for both autoimmune pancreatitis and chronic pancreatitis was elucidated for the first time in the world. Applications are expected for new treatments of chronic pancreatic inflammation and new preventive measures for pancreatic cancer.

Polymeric membranes

Permeation Mechanism of Water through Polymeric Membrane; Clarified for the First Time in the World Expectations for Development of Membranes with Functions, Such As Seawater Desalination - Kindai University

Associate Professor Noriyoshi Arai and his research group at the Mechanical Engineering Department at the Faculty of Science and Engineering of Kindai University have elucidated the mechanism of permeation through polymeric membranes. The findings of this research will be featured in the Journal of Membrane Science , on October 15, 2018 at 8:00 AM (JST).

figure of molecular simulation

Successful Use of AI Technology for Efficient Prediction of Physical Properties of Substances with Complex Molecular Structures

- The study demonstrated that machine learning can be applied to predict physical properties of functional materials that have complex structures. - For the first time in the world, machine learning methodology has been applied to the analysis of complex molecular structures of surfactants that are used in our immediate surroundings, such as detergents and cosmetic products.

World’s First Demonstration on Efficacy of Drug for Lung Cancer Genetic Mutation Diagnosed with Blood sample using cobas EGFR mutation test v2.Alleviating burden on patients through diagnosis with blood tests

World’s First Demonstration on Efficacy of Drug for Lung Cancer Genetic Mutation Diagnosed with Blood sample using cobas EGFR mutation test v2.Alleviating burden on patients through diagnosis with blood tests

[Key aspects of this study] - World’s first research findings that demonstrate efficacy and safety of a drug which is administered based on genetic screening results. - Efficacy demonstrated by a response rate of 55.1%, which represents the ratio of people whose tumor shrunk. - Potential for partial transition to blood test from endoscopic biopsy, which places a heavy burden on patients.

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“Japan University News” is an English-language news portal that provides an outlet for the latest news of Japanese Universities for a global audience. It provides an overview of the unique culture, prominent research and contributions to the global society of Japanese Universities for international media, stakeholders and other interested parties.

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