Revealing the mechanism of immunity activation by extracellular vesicles from lactobacillus: Leading to deep understanding of the bacteria in our daily food and insights into better intestinal environment -- Kindai University
Elucidated the mechanism of immune cell activation by extracellular vesicles of lactobacillus Identified outer surface proteins of extracellular vesicles that affect immune activation The findings of this research will lead to the development of technologies to improve intestinal environment and to maintain healthy physical functions.
Finding the source of pathogen infectivity in rice to reveal the mechanism of induction of immunity:A new insight into the development of disease-resistant plants -- Kindai University
Discovered a transcription factor called “OsERF101” that plays an important role in rice immunity Elucidated the mechanism by which rice pathogen recognition receptor activates immunity by recognizing the most important virulence factors of the pathogens. Expected that this research will contribute to a new development of disease-resistant plants.
World’s first! Identified pathogenic bacteria for autoimmune pancreatitis: A healthy intestinal environment may help prevent and treat autoimmune pancreatitis -- Kindai University
Discovered that intestinal barrier dysfunction exacerbates autoimmune pancreatitis The pathogenic bacterium of autoimmune pancreatitis, an intractable disease, was identified as an intestinal bacterium, Staphylococcus sciuri Suggested that maintenance of a healthy intestinal environment may lead to the prevention and treatment of autoimmune pancreatitis
A new program to classify solid tumors into eight genomic subtypes: Leading to predictive response analysis for cancer tumor ICI efficacy -- Kindai University
- Analyzing DNA data of approximately 10,000 cases, the team developed a new program to classify solid tumors into eight genomic subtypes - Demonstrated that these eight classifications were significantly associated with ICI efficacy - The results of this study will help predict response to ICI therapy on solid tumors and improve prognosis
Novel research on bacteria and fungi on face masks promotes the hygienic use of masks under the COVID-19 pandemic -- Kindai University
- The first research focused on the usage of masks and bacteria and fungi attached to the face-side and the outer-side of masks -Recommended avoiding repeated use of masks (no more than one day) for people with weak immunity since potentially harmful microbes were found -This study will provide new insights into the appropriate and hygienic use of face masks under the COVID-19 pandemic.
Contributing to lightning disaster prevention in Malaysia -- Selected for the FY2022 Science and Technology Research Partnership for Sustainable Development (SATREPS) Program
Our joint research on lightning disaster prevention has been selected for SATREPS Promoting this research in collaboration with ODA. Real-time 3D imaging of charge distribution in thunderclouds and forecasting of lightning activity based on the observation technology cultivated over the years, it aims to prevent and mitigate disaster in Malaysia where the annual lightning day exceeds 200 days.
Discovered “GT-7” compound induces cell death in pancreatic cancer cells - Expected for a new treatment approach different from the mechanisms of conventional anticancer drugs
Found that GT-7 induces apoptosis of pancreatic cancer cells with specific gene mutations.
Soka University Liaison Office in Nairobi Established as a Hub for Educational Exchanges in African Countries
As a part of the “Top Global University Project” led by the Ministry of Education, Culture, Sports, Science and Technology, the “University of Nairobi - Soka University Liaison Office” was established in the Education Building of the University of Nairobi in Kenya, Africa.
Curcumin prodrug CMG has beneficial effects on a mouse model of multiple sclerosis by modulating the gut flora -- Kindai University
CMG treatment for a mouse model of multiple sclerosis (MS) suppressed motor paralysis clinically and inflammation in the central nervous system (CNS) microscopically. CMG treatment altered the gut flora in the intestine and feces. Increases in several bacterial species correlated with the disease severity.
Functional bag “Peg” created through industry-academia cooperation to be launched in New York. Contributes to the recovery and promote SDGs with shark leather from Kesennuma, Miyagi, Japan
- Kindai University students and a leather brand "Atelier Shark" jointly developed a small functional bag that is useful in outdoor environments and in the event of disaster. The bags will be released in New York. - Lightweight blue shark leather from Kesennuma City, Miyagi, has excellent drip-proof and durability. Disseminating the benefits of the shark leather supports the reconstruction and ind
World-first research: bringing more insights into biodiversity -- A new technique to analyze genomic functions of wild and extinct animals -- Kindai University
Developed a new method that induces the reprogramming of the mammalian genome, including wild/endangered species, and induces the activation of genes that are specifically expressed in early embryos. The result brings insights into biodiversity, allowing analysis of genomic functions of extinct animals.
Next-generation prebiotic promotes selective growth of beneficial bacteria -- Paving the way for new treatments for refractory clostridioides difficile colitis -- Kindai University
Discovered that Galactosyl-β1, 4-L-Rhamnose (oligosaccharide) selectively promotes the growth of health-promoting bacteria. Identified the gene required for the growth promotion specific to bifidobacteria, utilizing oligosaccharide.